Legionnaires' disease is a severe form of pneumonia — lung inflammation usually caused by infection. Essendo il microrganismo ubiquitario, la malattia può manifestarsi con epidemie dovute ad un’unica fonte, con limitata esposizione nel tempo e nello spazio all’agente eziologico, oppure con una serie di casi indipendenti in un’area ad alta endemia o con casi sporadici senza un evidente raggruppamento temporale o geografico. La polmonite da Legionella ha dei sintomi che sono spesso indistinguibili dalle polmoniti causate da altri microrganismi e, per questo motivo, la diagnosi di laboratorio della legionellosi deve essere considerata complemento indispensabile alle procedure diagnostiche cliniche.

Older adults, smokers and people with weakened immune systems are particularly susceptible to Legionnaires' disease.The legionella bacterium also causes Pontiac fever, a milder illness resembling the flu. The most important host defense mechanism against invading intracellular opportunistic bacteria is phagocytosis by macrophages, followed by intracellular killing and digestion of the microbes. A single copy of these materials may be reprinted for noncommercial personal use only.

Legionnaires' disease is a severe form of pneumonia — lung inflammation usually caused by infection. By continuing you agree to the Copyright © 2020 Elsevier B.V. or its licensors or contributors. It frequently begins with the following signs and symptoms:By the second or third day, you'll develop other signs and symptoms that can include:Although Legionnaires' disease primarily affects the lungs, it occasionally can cause infections in wounds and in other parts of the body, including the heart.A mild form of Legionnaires' disease — known as Pontiac fever — can produce fever, chills, headache and muscle aches. Il problema sorge quando il batterio si diffonde nelle tubature (come a casa, nei luoghi pubblici o in ufficio). Legionella pneumophila is an intracellular, pleomorphic, Gram-negative bacterium with a definite iron requirement, reflected by an inability to grow on medium in the absence of iron supplementation. Test diagnostici per la legionellosi dovrebbero essere idealmente eseguiti in tutti i seguenti casi di polmonite:

Il batterio è inoltre pleomorfo, non alcool-acido resistente, asporigeno, non capsulato ed aerobio obbligato, in quanto necessita di ossigeno per sopravvivere. However, artificial water systems which provide environments conducive to the growth and dissemination of Legionellarepresent the most likely sources of disease. Nello specifico, a seconda della forma in cui si presenta, può portare a: Outbreaks have been linked to:Besides by breathing in water droplets, the infection can be transmitted in other ways, including:Not everyone exposed to legionella bacteria becomes sick.

Legionella pneumophila, or L. pneumophila, is a species of bacteria that causes legionellosis, also known as Legionnaire’s disease. La legionellosi viene normalmente acquisita per via respiratoria mediante inalazione, aspirazione o microaspirazione di aerosol contenente Il batterio dà infatti origine alla legionellosi, una malattia che si manifesta con diversi sintomi come febbre, brividi e tosse. Legionella pneumophila è un sottile batterio Gram-negativo, di forma cocco-bacillare e dotato di mobilità grazie alla presenza di uno o due flagelli.

La Legionellosi, detta anche Malattia dei legionari, è un’infezione polmonare causata dal batterio ScienceDirect ® is a registered trademark of Elsevier B.V.URL: https://www.sciencedirect.com/science/article/pii/S0065242310500027URL: https://www.sciencedirect.com/science/article/pii/B9783437222528500124URL: https://www.sciencedirect.com/science/article/pii/B9780323043281500140URL: https://www.sciencedirect.com/science/article/pii/B9780444529107000416URL: https://www.sciencedirect.com/science/article/pii/B9780128053515000065URL: https://www.sciencedirect.com/science/article/pii/B9780323045797000010URL: https://www.sciencedirect.com/science/article/pii/B9780323548434000052URL: https://www.sciencedirect.com/science/article/pii/B9780123971692000901URL: https://www.sciencedirect.com/science/article/pii/B9780123739476002282URL: https://www.sciencedirect.com/science/article/pii/B9780123809209000250Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, 2017Maryam Nesvaderani MBBS, BSC (HONS), ... Michael R. Cox FRACS, MS, MBBS, in Gastrointestinal Diseases and their Associated InfectionsElizabeth J. Nazarian, ... Kimberlee A. Musser, in The Laboratory Rabbit, Guinea Pig, Hamster, and Other RodentsArmstrong and Haas, 2007; Padilla-Carlin et al., 2008Armstrong and Haas, 2007; Davis et al., 1982; Winn et al., 1982Berendt et al., 1980; Dournon and Rajagopalan, 1988; Fitzgeorge et al., 1983Berendt et al., 1980; Davis et al., 1982, 1983a, 1983b; Fitzgeorge et al., 1983Blander and Horwitz, 1991, 1993; Klein et al., 1984; Weeratna et al., 1994Edelstein et al., 1982; McDade et al., 1977; Meenhorst et al., 1983Blander and Horwitz 1991, 1993; Breiman and Horwitz 1987Blander and Horwitz, 1991, 1993; Breiman and Horwitz, 1987Dournon and Rajagopalan, 1988; Dournon et al., 1986; Edelstein et al., 1999, 2001a, 2001b; Garcia-de-Lomas et al., 1998ScienceDirect ® is a registered trademark of Elsevier B.V. Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium of the genus Legionella.

La legionella è un batterio presente negli ambienti naturali e artificiali: acque sorgive, comprese quelle termali, fiumi, laghi, fanghi, ecc.

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